方家松

一、基本信息

教授博士生导师上海深渊科学工程技术研究中心主任。联系方式：电话14782382788； 邮箱：jsfang@shou.edu.cn

二、学术兼职

Deep-Sea Research I 主编（Editor-in-Chief）

Frontiers in Marine Sciences 副主编（Associate Editor）

中国海洋生物资源委员会委员、中国地质微生物学专业委员会委员

科技部深渊生物专项首席科学家

2009年教育部人才计划特聘教授

2016年第十二批国家创新人才项目

三、主要教育及工作经历

2024.01—现在 上海海洋大学beat365官方网站特聘教授

2017.01—2024.01 上海海洋大学海洋科学学院特聘教授

2012.05—现在 夏威夷太平洋大学海洋学教授

2008.09—2012.04 夏威夷太平洋大学海洋学副教授

2001.08—2008.09 衣阿华州立大学助理教授

1995.08—2001.08 密执安大学环境科学与工程系助理科学家

1993.05—1995.08 迈阿密大学微生物系博士后

1993年获德州农工大海洋学博士

1989年获路易斯安娜州立大学地球化学硕士学位

1987 北京石油勘探开发科学研究院硕士研究生

三、研究兴趣及专长

主要研究领域为深海和深部生物圈嗜高压微生物和细菌芽孢的地质微生物学和生物地球化学，研究手段包括传统的以实验室分离培养为基础的研究方法和非传统的分子微生物学、生物标志化合物和稳定同位素方法。方家松长期从事深海嗜高压微生物生态学和海洋碳循环研究，形成了系统的结合微生物学、生态学、酶学和海洋化学的创造性学术成果，建立了微生物（尤其是深海嗜高压微生物）介导的海洋碳循环模型：“海洋碳-菌链”（POM-DOM-Piezophilic Microorganism Continuum; PDPMC）。这个模型为研究海洋碳循环动力学过程（mechanistic processes）提供了一个指导性框架，为预测全球变化下的海洋碳循环动力学提供了理论基础。近年来，方家松教授在深海和深部生物圈嗜高压细菌、革兰氏阳性产芽孢菌、深海和深部生物圈嗜高压细菌和革兰氏阳性菌芽孢的高压C 、H同位素地球生物化学和团簇同位素科学等方面取得了一系列研究成果。

四、获奖

2003年获美国航天航空局（NASA）、美国工程教育学会、大学空间研究协会授予的《杰出研究奖》（Research Excellence Award）。

五、近期基金

• 国家重点研发计划“深海关键技术与装备”专项项目“深渊生物学资源勘探、获取和开发的前沿技术体系研究”, 1853万, 2018.8–2021.12

• 国家自然科学基金委微生物驱动的水圈元素循环重点基金“微生物驱动的深海碳循环机制和生态过程研究”，300万。 2020.1–2023.12

• 深部生物圈革兰氏阳性产孢子细菌孢子化以及孢子活化的定量分析和碳同位素分馏研究，69万，国家自然科学基金委面上项目，2018.1–2021.12

• 高压条件下嗜高压细菌脂类生物合成过程中的碳同位素分馏研究，100万，国家自然科学基金委面上项目，2014.1–2017.12

• 国家自然科学基金委重点基金“评价嗜高压细菌在南海深部碳循环中的作用”，295万，国家自然科学基金委重点项目，2014.1–2017.12

六、主讲课程

Microbial Oceanography （全英语）

七、科考航次和载人深潜经历

7/17-9/15/2016 首席科学家，张蹇号新不列颠海沟航次

1/26-3/30/2014 Shore-based scientist, IODP Expedition 349, Opening of the South China Sea and its implications for southeast Asian tectonics, climates, and deep mantle processes since the late Mesozoic

7/22-9/21/2012 Shore-based scientist, IODP Expedition 337, Deep Coalbed Biosphere off Shimokita, Microbial processes and hydrocarbon system associated with deeply buried coalbed in the ocean

6/10 – 6/19, 2005 Yokosuka/Shinkai 6500 Nankai Bio-Symbiont Cruise to the Nankai Trough

5/19 – 5/29, 1992 DSRV Alvin Gulf of Mexico hydrocarbon seep cruise

Dive #3131, GB 386 (Gulf of Mexico), 1,921 ft

Dive #3137, GC 272 (Gulf of Mexico), 2,349 ft

8/19 – 8/27, 1992 Johnson Sea-Link I Gulf of Mexico hydrocarbon seep cruise

9/12 – 9/19, 1991 Johnson Sea-Link I Gulf of Mexico hydrocarbon seep cruise

2/26 – 3/12, 1991 R/V Gyre Gulf of Mexico core ring cruise

八、论文

1. Cui, J., Yu, Z., Mi, M., He, L., Yao, P., Fang, J., Sun W., 2020. Occurrence of Halogenated Organic Pollutants in Hadal Trenches of the Western Pacific Ocean. Environ. Sci. Technol. 54, 15821–15828

2. Wang, H., Chen, J., Wang, Yu., Fang, J., Fang, Y., 2020.  Research and analysis of pressure-maintaining trapping instrument for macro organisms in hadal trenches. J. Mar. Sci. Engineering. 8, 596; doi:10.3390/jmse8080596

3. Mao, H., Wei, Y., Gao, Y., Pei, J., Zhang, Y., Fang, J., 2020. Metabacillus sediminilitoris sp. nov., a marine bacterium isolated from a tidal sediment. Int J Syst Evol Microbiol 2020, DOI:

4. Xue, J., Fang*, J., Zhang, H., Wei, Y., Wang, L., Liu, R., Cao, J., 2020. Complete genome sequence of a piezophilic bacterium Salinimonas sediminis N102T, isolated from deep-sea sediment of the New Britain Trench. Marine Genomics, in press

5. Xu, Y., Jia, Z., Xiao, W., Fang, J., Wang, Y., Luo, M., Wenzhöfer, F., Rowden, A.A., Glud, R.N., 2020., Glycerol dialkyl glycerol tetraethers in surface sediments from three Pacific trenches: Distribution, source and environmental implications. Org. Geochem. 147.104079

6. Liu, R., Wang, Z., Wang, L., Li, Z., Fang, J., Wei, X., Wei, W., Cao, J., Wei, Y., Xie, Z., 2020. Bulk and active sediment prokaryotic communities in the Mariana and Mussau Trenches. Frontiers in Microbiology, doi: 10.3389/fmicb.2020.01521

7. Zhao, W., Fang, J., Huang, X., Zhang, Y., Liu, W., Wang, Y., Zhang, L., 2020. Carbon and hydrogen isotope fractionation in lipid biosynthesis by Sporosarcina sp. DSK25. Geochemical Perspective Letters 14, 9-13

8. Zhang, Y., Gao, Y., Pei, J., Cao, J., Xie, Z., Liu, R., Wang, L., Wei, Y., Fang, J., 2020. Muricauda hadalis sp. nov., a novel piezophile isolated from hadopelagic water of the Mariana Trench and reclassification of Muricauda antarctica as a later heterotypic synonym of Muricauda teanensis. Int J Syst Evol Microbiol 2020, DOI: 10.1099/ijsem.0.0042 88

9. Li, J., L., Su, M. Sun, Q. Li, H. Zhou, J. Fang*, 2020. Elucidating the biomineralization of low-temperature hydrothermal precipitates with varying Fe, Si contents: Indication from ultrastructure and microbiological analyses. Deep–Sea Research I 157, 103208

10. Yan, F., J Fang, J Cao, Y Wei, R Liu, L Wang, Z Xie.2020. Halomonas piezotolerans sp. nov., a multiple-stress-tolerant bacterium isolated from a deep-sea sediment sample of the New Britain Trench. Int J Syst Evol Microbiol, doi.org/10.1099/ijsem.0.004069

11. Liu, Y., J. Fang*, Z., Jia, S. Chen, L. Zhang, W. Cao, 2020. DNA stable-isotope probing reveals potential key players for microbial decomposition and degradation of diatom-derived marine particulate matter. MicrobiologyOpen, DOI: 10.1002/mbo3.1013

12. Liu, Y., J. Fang*, 2020. Coastal Lakes as a Buffer Zone for the Accumulation and Redistribution of Plastic Particles from Continental to Marine Environment: A Case Study of the Dishui Lake in Shanghai, China. Applied Sciences 10, 1974; doi:10.3390/app10061974

13. Ding, W., Liu, P., Xu, Y., Fang, J., & Cao, J., 2019. Polyphasic taxonomic analysis of Parasedimentitalea marina gen. nov., sp. nov., a psychrotolerant bacterium isolated from deep sea water of the New Britain Trench. FEMS Microbiol Lett 366, fnaa004. DOI: 10.1093/femsle/fnaa004

14. Wei, Y.,Wang, K.,Pei, J., Zhang, Y., Fang, J., 2019. Confluentibacter sediminis sp. nov., isolated from the junction between the ocean and a freshwater lake and emended description of the genus Confluentibacter. Int J Syst Evol Microbiol, doi.org/10.1099/ijsem.0.003665

15. Wei, Y., Cao, J., Mao, M., Pei, J., Liu, R., Fang, J., 2019. Marinomonas shanghaiensis sp. nov., isolated from the junction between an ocean and a freshwater lake. Int J Syst Evol Microbiol., 69: 805-810

16. Wei, Y., Cao, J., Yao, H., Mao, H., Zhu, K., Li, M., Liu, R., Fang, J., 2019. Paracoccus sediminilitoris sp. nov., isolated from a tidal flat sediment. Int J Syst Evol Microbiol 69: 1035-1040

17. Wei, Y., Mao, M., Wang, K., Yao, H., Zhang, Y., Cao, J., Xie, Z., Fang, J., 2019. Algoriphagus litoralis sp. nov., isolated from the junction between the ocean and a freshwater lake. Antonie van Leeuwenhoek 112: 1545-1552

18. Cao, J., Liu, P., Liu, R., Su, H., Wei, Y., Liu, R., and Fang, J., 2019. Marinobacter profundi sp. nov., a slightly halophilic bacterium isolated from a deep-sea sediment sample of the New Britain Trench, Antonie van Leeuwenhoek 112: 425-34

19. Cao, J., Ding, W., Lai, Q., Wei, Y., Liu, R., Wang, L., and Fang, J., 2019. Alteromonas indica Lin et al. 2018 is a later heterotypic synonym of Salinimonas sediminis Cao et al. 2018, International Journal of Systematic and Evolutionary Microbiology 69: 1423-25

20. Cao, J., Ding, W., Lai, Q., Wei, Y., Liu, R., Wang, L., and Fang, J., 2019. Salinimonas sediminis sp. nov., a piezophilic bacterium isolated from a deep-sea sediment sample from the New Britain Trench, International Journal of Systematic and Evolutionary Microbiology 68: 3766-71

21. Liu, P., Ding, W., Lai, Q., Liu, R., Wei, Y., Wang, L., Xie, Z., Cao, J., and Fang, J. 2019. Physiological and genomic features of Paraoceanicella profunda gen. nov., sp. nov., a novel piezophile isolated from deep seawater of the Mariana Trench. MicrobiologyOpen. DOI: 10.1002/mbo3.966

22. Cao, J., Wei, Y., Lai, Q., Wu, Y., Deng, J., Li, J., Liu, R., Wang L., and Fang J., 2019. Georhizobium profundi gen. nov., a piezotolerant bacterium isolated from a deep-sea sediment sample of the New Britain Trench. Int J Syst Evol Microbiol.. DOI: 10.1099/ijsem.0.003766

23. Wang, N., Shen, S., Sun, W., Ding, P., Zhu, S., Yi, W., Yu, Z., Sha, Z., Mi, M., He, L., Fang*, J., Liu, K., Xu, X., Druffel, E., 2019. Penetration of Bomb 14C into the Deepest Ocean Trench. Geophys. Res. Lett. DOI:10.1029/2018GL081514

24. Fang*, J., Dasgupta, S., Zhang, L., and Zhao, W., 2019. Lipid biomarkers in geomicrobiology: analytical techniques and applications. In: Analytical Geomicrobiology, A Handbook of Instrumental Techniques, ed. by Janice P. Kenney, Harish Veeramani, Daniel S. Alessi, Cambridge University Press. P. 341-359

25. Jamieson, A.J., Fang, J., and Cui, W., 2018. Exploring the hadal zone: recent advances in hadal science and technology. Deep-Sea Research II 155, 1-3

26. Cao, J., Lai, Q., Liu, P., Wei, Y., Wang, L., Liu R., and Fang*, J., 2018. Salinimonas sediminis sp. nov., a piezophilic bacterium isolated from a deep-sea sediment sample from the New Britain Trench. Int J Syst Evol Microbiol. 68(12): 3766-3771

27. 方家松、李江燕、张利，2018. 海底CORK观测３０年: 发展、应用与展望。地球科学进展 32, 12，1297-1306

28. 方家松、许元棋、李江燕、张利，2018. 深海站探和海底观测50年。大洋站探50年，中国大洋发现计划办公室、同济大学海洋地质国家重点实验室编著，同济大学出版社

29. 赵伟强, 方家松, 黄咸雨等. 生长压力对Bacillus subtilis 磷脂脂肪酸 同位素分馏的影响[J]. 上海海洋大学学报, 2018, 27(6)

30. Wei Y., Cao, J., Mao, H., Zhu, K., Li, M., Liu, R., Fang* J. 2018. Paracoccus sediminilitoris sp. nov., isolated from a tidal flat on the East China Sea. Int J Syst Evol Microbiol. 69(4): 1035-1040

31. Wei Y., Cao, J., Mao, H., Liu, R., Fang,* J. 2018. Marinomonas shanghaiensis sp. nov., isolated from the junction between the ocean and a freshwater lake. Int J Syst Evol Microbiol. 69(3): 805-810

32. Guan, H., Chen, L., Luo, M., Liu, L., Mao, S., Ge, H., Zhang, M., Fang*, J., Chen, D. 2018. Composition and origin of lipid biomarkers in the surface sediments from the southern Challenger Deep, Mariana Trench.  Geoscience Frontiers 10, 351-360

33. Wei, Y., Fang*, J., Xu, Y., Zhao, W., and Cao, J., 2018. Corynebacterium hadale sp. nov. isolated from Hadopelagic Water of the New Britain Trench. Int’ J. Systematic and Evolutionary Microbiology 68(5): 1474-1478

34. Wei, Y., Zou, W., Mao, H., Fang*, J., and Blom, j., 2018. Pseudomonas abyssi sp. nov. isolated from the Abyssopelagic Water of the Mariana Trench. Int’ J. Systematic and Evolutionary Microbiology. 68(8): 2462-2467

35. Liu, R., Wang, L., Liu, Q., Wang, X., Li, Z., Fang*, J., Zhang, L., and Luo, M., 2018. Depth-resolved Distribution of Particle-attached and Free-living Bacterial Communities in the Water Column of the New Britain Trench. Frontiers in Microbiology. doi: 10.3389/fmicb.2018.00625

36. Liu, Q., Fang*, J., Li, J., Zhang, L., Xie, B.-B., Chen, X.-L., and Zhang, Y.-Z., 2018. Depth-resolved variations of cultivable bacteria and their extracellular enzymes in the water column of the New Britain Trench. Frontiers in Microbiology, doi: 10.3389/fmicb.2018.00135

37. Fang, J., Li, J., and Zhang, L., 2018. The 30 Years of Seafloor CORK Borehole Observatories: Development, Applications and Future Perspectives. Advances in Earth Sciences, 32

38. Xu, Y., Ge, H., and Fang*, J., 2018. Biogeochemistry of the hadal trenches: recent developments and Future perspectives, Deep Sea Research II 155, 19-26

39. Cao, J., Birien, T., Gayet, N., Huang, Z., Shao, Z., Jebbar, M., and Alain, K., 2017. Desulfurobacterium indicum sp. nov., a thermophilic sulfur-reducing bacterium from the Indian Ocean. Int J Syst Evol Microbiol 67, 1665-1668. DOI: 10.1099/ijsem.0.001837

40. Liu, R., Wang, L., Wei, Y., Fang*, J., 2017. The hadal biosphere: recent insights and new directions. Deep-Sea Research II, doi.org/10.1016/j.dsr2.2017.04.015

41. Fang*, J., Kato, C., Runko, G. M., Nogi, Y., Hori, T., Li, J., Morono, Y., Inagaki, F., 2017. Predominance of viable spore-forming piezophilic bacteria in high-pressure enrichment cultures from ~1.5 to 2.4 km-deep coal-bearing sediments below the ocean floor. Frontiers in Microbiology, 8:137. doi: 10.3389/fmicb.2017.00137

42. Dasgupta, D., and Fang*, J., 2017. Mitochondrial clock: moderating evolution of early eukaryotes in light of the Proterozoic oceans. Biologia 71, 843-852, 72/5: 586

43. Wei Y., Cao J, Fang* J, Kato C, Cui W. 2017. First complete genome sequence of Marinilactibacillus piezotoleransstrain 15R, a marine lactobacillus isolated from coal-bearing sediment 2.0 kilometers below the seafloor, determined by PacBio single-molecule real-time technology. Genome Announcement 5, e01625-16. https://doi.org/10.1128/genomeA.01625-16

44. Wei, Y., Cao, J., Fang*, J., Kato, C., Cui, W., 2017. Complete Genome Sequence of Bacillus subtilis strain 29R7-12, a Piezotolerant Bacterium Isolated from Coal-Bearing Sediment 2.4 km Below the Seafloor. Genome Announcement 5, e01621-16

45. Liu, Q., Li, J., Wei, B., Zhang, X., Zhang, L., Zhang, Y., and Fang*, J., 2016. Leeuwenhoekiella nanhaiensis sp. nov., isolated from the deep-sea water of the South China Sea. International Journal of Systematic and Evolutionary Microbiology 66, 1352-1357

46. Li, J., Zhou, H., Fang*, J., Wu, Z., Peng, X., 2016. Microbial distribution in a hydrothermal plume of the Southwestern Indian Ridge. Geomicrobiology J., 33, 401-415

47. Li, J., Wei, B., Wang, J., Liu, Y., Dasgupta, S., Zhang, L., Fang*, J., 2015. Variation in abundance and community structure of particle-attached and free-living bacteria in the South China Sea. Deep-Sea Research II 122, 64-73

48. Kim, S.-H., Tian, Q., Fang, J., and Sung, S., 2015. Removal of 17-β estradiol in water by sonolysis. International Biodeterioration & Biodegradation, 102, 11–14

49. Wei, B., Li, J., Zhang, L., Liu, Y., Fang*, J., 2015. The 234Th:238U disequilibria and their applications in studying marine particulates dynamics. Marine Geology Frontiers 31, 1-9

50. Fang*, J., Zhang, L., Li, J., Kato, C., Zhang, Y., Tamburini, C., Wang, G., Wang, F., and Dang, H., 2015. The POM-DOM piezophilic microorganism continuum (PDPMC) – the role of piezophilic microorganisms in the global ocean carbon cycle. Science China (Earth Sciences) 57, 1-10

51. Nilsen, F., Hyrenbach, K.D., Fang, J., and Jensen, B., 2014. Use of indicator chemicals to characterize the plastic fragments ingested by Laysan albatross. Marine Pollution Bulletin 87, 230–236

52. Li, J., Zhou, H., Fang*, J., Sun, Y., and Dasgupta, S., 2014. Microbial distribution in different spatial positions within the walls of a black sulfide hydrothermal chimney. Mar. Ecol. Prog. Ser. 508, 67–85

53. Fang*, J., Li, C., Zhang, L., Kato, C., and Bartlett, D. G., 2014. Hydrogen isotope fractionation in lipid biosynthesis by the piezophilic bacterium Moritella japonica DSK1. Chemical Geology 367, 34–38

54. Wang, J., Li, J., Dasgupta, S., Zhang, L., and Fang*, J., 2014. Alterations in membrane lipid composition of piezophilic Gram-positive bacterium Sporosarcina sp. DSK25 at high pressures. Lipids, 49, 347–356

55. Zhang, L., Fang*, J., and Joeckel, A.M., 2013. Microbial biomass and community structure in alkaline lakes of the Nebraska Sand Hills, USA. Chemical Geology 356, 171–180

56. Dasgupta, S., Fang*, J., Brake, S. S., Hasiotis, S.T., and Zhang, L., 2013. Stable isotope fractionation in lipids of Euglena-dominated biofilms from an acid mine drainage site: interpretation of environmental conditions, microbial physiology, and biosynthetic pathways. Chemical Geology 354, 15–21

57. Dasgupta, S., Fang*, J., Li, J., Zhang, L., Wang, J., and Wei, B., 2013. Microeukaryotes in modern acid mine drainage: biodiversity, physiology, and biogeochemistry and clues to the evolution of life and the early Earth environment. Quaternary Science, 33, 68–78

58. Li, J., Sun, Y., Fang, J., Chen, S., P. X., Wu, Z., and Zhou, H., 2013. Aerobic and anaerobic ammonia-oxidizing microorganisms in low-temperature hydrothermal Fe-Si-rich precipitates of the southwestern Pacific Ocean. Geomicrobiology Journal DOI: 10.1080/ 01490451.2013.802397

59. Shamik Dasgupta, 方家松；李江涛；张利；王嘉妮；韦兵兵, 2013. 现代酸性矿山废水环境中的真核微生物：生物多样性、生理学、生物地球化学特征及其对古环境和早期生命演化的指示. 第四纪研究, 33(1),  68-78

60. Bazylinski, D.A., Williams, T.J., Lefèvre, C.T., Trubitsyn, D., Fang, J., Beveridge, T.J., Moskowitz, B.M., Ward, B., Schübbe, S., Dubbels, B.L., and Simpson, B. 2012. Magnetovibrio blakemorei, gen. nov. sp. nov., a new magnetotactic bacterium (Alphaproteobacteria: Rhodospirillaceae) isolated from a salt marsh. International Journal of Systematic and Evolutionary Microbiology 63, 1824–1833

61. Li, J., Zhou, H., Peng, X., Wu, Z., Chen, S., and Fang, J., 2012. Microbial diversity and biomineralization in low-temperature hydrothermal iron–silica-rich precipitates of the Lau Basin hydrothermal field. FEMS Microbiology Ecology 81, 205–216

62. Dasgupta, S., Fang*, J., Brake, S.S., Hasiotis, S.S., and Zhang, L., 2012. Biosynthesis of sterols and wax esters by Euglena of acid mine drainage biofilms: Implications for eukaryotic evolution and the early Earth. Chemical Geology 306–307, 139–145

63. Wu, X., Fang, J., Xiang, M.O., Ling, H.E., Xin-Ting, S., 2011. Driving mechanisms for the DOC increases in surface waters released from Northern Peatlands under global change. Earth Science Frontiers 18, 72-78

64. Shelton, J.M., Kim, L., Fang, J., Ray, C., and Yan, T., 2011. Assessing the severity of rainfall derived infiltration and inflow and sewer deterioration based on the flux stability of sewage markers. Environmental Science and Technology. 45, pp 8683–8690

65. Fang, J., and L. Zhang, 2011. Piezophilic bacteria. In: The Encyclopedia of Geobiology, the Springer Encyclopedia of Earth Sciences Series (J. Reitner and V. Thiel, eds.), Springer-Verlag , Heidelberg , Germany

66. Fang, J., and L. Zhang, 2011. Genomics, metagenomics, and microbial oceanography—A sea of opportunities. Science China (Earth Sciences) 54, 473–480

67. Fang, J., and L. Zhang, 2011. Explore the deep biosphere. Science China (Earth Sciences) 54, 1–9

68. Fang, J., L. Zhang, and Bazylinski, D.A., 2010. The deep-sea piezosphere and piezophiles: geomicrobiology and biogeochemistry. Trends in Microbiology 18, 413-422

69. Fang, J., and Kato, C., 2010. Deep-sea piezophilic bacteria: geomicrobiology and biotechnology. In: Geomicrobiology: Biodiversity and Biotechnology (S. K. Jain, ed.), pp. 47-77. Blackwell Publishing

70. Fang, J., and Bazylinski, D. A., 2008. Deep-sea geomicrobiology. In: High-Pressure Microbiology (C. Michiels and D. H. Bartlett, eds.), American Society for Microbiology, Washington, D.C. pp. 237-264

71. Fang, J., and Kato, C., 2008. Deep-sea piezophilic bacteria, ocean carbon cycle, and climate change. In: the Encyclopedia of Global Warming and Climate Change (S. George Philander, ed.), Golson Books, Ltd., 2:557-558

72. Fang, J., and Kato, C., 2007. FAS or PKS, lipid biosynthesis and stable carbon isotope fractionation in deep-sea piezophilic bacteria. In: Communicating Current Research and Educational Topics and Trends in Applied Microbiology (2007), The Formatex Microbiology Book Series (A. Méndez-Vilas, ed.), Formatex Center, Spain, pp. 190-200

73. Fang, J., Gupta, S. D., Hasiotis, S. T., Brake, S. S., and Bazylinski, D. A., 2007. Microbial community structure of a stromatolite from an acid mine drainage system, implications for the role of microeukaryotes in the formation of ancient Fe-rich stromatolites. Chemical Geology 243, 191-204

74. Fang, J., Lyon, D. Y., Alvarez, P. J. J., Wiesner, M., and Dong, J., 2007. Effect of a fullerene water suspension on bacterial phospholipids and membrane phase behavior. Environmental Science and Technology 41, 2636-2642

75. Fang, J., Arakawa, S., Kato, C., and Schouten, S., 2006. Microbial diversity of cold-seep sediments in Sagami Bay, Japan determined by 16S rDNA and lipid analyses. FEMS Microbiology Ecology 57, 429-441

76. Fang, J., Uhle, M., Billmark, K., Bartlett, D. H., and Kato, C., 2006. Fractionation of carbon isotopes in biosynthesis of fatty acids by a piezophilic bacterium Moritella japonica DSK1. Geochimica et Cosmochimica Acta 70, 1753-1760

77. Fang, J., Chan, C., Joeckel, R. M., Huang, Y., Wang, Y., Bazylinski, D. A., and Moorman, T. B., 2006. Biomarker analysis of microbial diversity in sediments of a saline groundwater seep of Salt Basin, Nebraska. Organic Geochemistry 37, 912-931

78. Fang, J., 2006. Book review (invited). Energy, Waste and the Environment: a Geochemical Perspective, by R. Gieré and P. Stille. Geoderma 131, 251-253

79. Fang, J., Lovanh, N., and Alvarez, P. J., 2004. The use of isotopic and lipid analysis techniques linking toluene degradation to specific microorganisms: applications and limitations.  Water Research 38, 2529-2536

80. Fang, J., Kato, C., Sato, T., Chan, O., Agarkar, N., and McKay, D. S., 2004. Polyunsaturated fatty acids in piezophilic bacteria: biosynthesis or dietary uptake? Comparative Biochemistry and Physiology B 137, 455-461

81. Fang, J., Chan, O., Kato, C., Sato, T., Peeples, T., and Niggemeyer, K., 2003. Phospholipid fatty acid profiles of piezophilic bacteria from the deep sea. Lipids 38, 885-887

82. Namocatcat, J. A., Fang, J., and Barcelona, M. J., 2003. Biogeochemical evidence of intrinsic bioremediation in a shallow sand aquifer contaminated with jet fuel hydrocarbons. Journal of Contaminant Hydrology 67, 177-194

83. Zhang, C. L., Li, Y., Ye, E., Fong, J., Peacock, A., Fang, J., Lovley, D., and White, D.C., 2003. Carbon isotopic signatures of fatty acids in Geobacter metallireducens and Shewanella putreficiens. Chemical Geology 195, 17-28

84. Fang, J., and Barcelona, M. J., 2003. Coupled oxidation of aromatic hydrocarbons by horseradish peroxidase and hydrogen peroxide. Chemosphere 50, 105-109

85. Fang, J., Kawamura, K., Ishimura, Y., and Matsumoto, K., 2002. Carbon isotopic composition of fatty acids in the marine aerosols from the western North Pacific: Implication for the source and atmospheric transport.  Environmental Science and Technology 36, 2598-2604

86. Fang, J., Barcelona, M. J., Abrajano, T. A., Kato, C., and Nogi, Y., 2002. Isotopic composition of fatty acids isolated from the extremely piezophilic bacteria from the Mariana Trench at 11,000 meters. Marine Chemistry 80, 1-9

87. Fang, J., and Kato, C., 2002. Piezophilic bacteria: taxonomy, diversity, adaptation, and potential biotechnological applications, pp. 47-80. In: Recent Advances in Marine Biotechnology (M. Fingerman, ed.), vol. 8, Science Publishers, Inc. Enfield

88. Zhang, C. L., Ye, Q., Anna-Louise Reysenbach, Götz, D., Peacock, A. White, D. C., Horita, J., Cole, D. R., Fong, J., Pratt, L., Fang, J., and Huang, Y., 2002. Carbon isotopic fractionations associated with thermophilic bacteria Thermotoga maritima and Persephonella marina. Environmental Microbiology 4, 58-64

89. Fang, J., Barcelona, M. J., and Alvarez, P. J., 2000. Phospholipid patterns of five pseudomonad archetypes for different aerobic toluene degradation pathways. Bioremediation Journal 4, 181-185

90. Fang, J., Barcelona, M. J., and Semrau, J., 2000. Characterization of methanotrophic bacteria on the basis of intact phospholipid profiles. FEMS Microbiology Letters 189, 67-72

91. Fang, J., Barcelona, M. J., and Alvarez, P. J., 2000. A direct comparison between fatty acid analysis and intact phospholipid profiling for microbial identification. Organic Geochemistry 31, 881-887

92. Fang, J., Barcelona, M. J., and Alvarez, P. J., 2000. Phospholipid compositional changes of five pseudomonad archetypes grown with and without toluene. Applied Microbiology and Biotechnology 54, 382-389

93. Fang, J., Barcelona, M. J., Krishnamurthy, R. V., and Atekwana, E. A., 2000. Stable carbon isotope biogeochemistry of an aquifer contaminated with fuel hydrocarbons. Applied Geochemistry 15, 157-169

94. Fang, J., Barcelona, M. J., Kato, C., and Nogi, Y., 2000. Biochemical function and geochemical significance of novel phospholipids isolated from extremely barophilic bacteria from the Mariana Trench at a depth of 11,000 meters. Deep-Sea Research I 47, 1173-1182

95. Fang, J., and Barcelona, M. J., 1999. Determination of organic acids in ground water by liquid chromatography/ atmospheric pressure chemical ionization/mass spectrometry. Analytical Letters 32, 1459-1473

96. Fang, J., and Barcelona, M. J., 1998. Biogeochemical evidence for community changes associated with hydrocarbon contamination in a sand aquifer.  Organic Geochemistry 29, 899-907

97. Fang, J., and Barcelona, M. J., 1998. Structural determination and quantitative analysis of bacterial phospholipids using liquid chromatography/electrospray ionization/mass spectrometry.  Journal of Microbiological Methods 33, 23-35

98. Xie, G., Barcelona, M. J., and Fang, J., 1998. Measurement and quantification of TPH by a GC/MS method and comparison with EPA 418.1 and PetroFlag® based on sediment samples from a contaminated site. Analytical Chemistry 71, 1899-1904

99. Fang, J., Barcelona, M. J., and West, C., 1997. The use of aromatic acids and phospholipid ester-linked fatty acids for delineation of processes affecting an aquifer contaminated with JP-4 fuel, pp. 65-76. In: Molecular Markers in Environmental Geochemistry (R P. Eganhouse, ed.). American Chemical Society, Washington, D.C.

100. Mayer, L. M., Chen, Z., Findlay, R. H., Fang, J., Sampson, S., Self, R. F., Jumars, P. A., Quetel, C., and Donard, O. F., 1996. Bioavailability of sedimentary contaminants subject to deposit-feeder digestion. Environmental Science and Technology 30, 2641-2645

101. Fang, J., and Findlay, R. H., 1996. The use of a classic lipid extraction method for simultaneous recovery of organic pollutants and phospholipids.  Journal of Microbiological Methods 27, 63-71

102. Yu, Y., Wade, T. L., Fang, J., Brooks, J. M., and McDonald, S., 1995. Production of PAH metabolites in Antarctic fish (Notothenia gibberifrons) dosed with diesel fuel Arctic and its implications to environmental pollution monitoring.  Archive of Environmental Contamination and Toxicology 29, 241-246

103. Abrajano, T. A., Murphy, D., Fang, J., and Comet, P. A., 1994. 13C/12C ratios in individual fatty acids of marine mytilids with and without bacterial symbionts. Organic Geochemistry 21, 611-618

104. Fang, J., Abrajano, T. A., Comet, P. A., Brooks, J. M., and Sassen, R., 1993. Gulf of Mexico hydrocarbon seep communities: IX.  Isotope fractionation during fatty acid biosynthesis of seep mytilids and vestimentiferans: implications for symbiotic processes. Chemistry Geology 109, 271-279

105. Fang, J., Comet, P. A., Wade, T. L., and Brooks, J. M., 1993. Non-methylene-interrupted fatty acids in the Gulf of Mexico hydrocarbon seep mytilids: occurrence and significance. Comparative Biochemistry and Physiology B 104, 287-291

106. Fang, J., Comet, P. A., Wade, T. L., and Brooks, J. M., 1992. Gulf of Mexico hydrocarbon seep communities: IX.  Sterol biosynthesis of seep mussels and its implications for host-symbiont association. Organic Geochemistry 18, 861-868

107. Fang, J., Comet, P. A., Brooks, J. M., and Sassen, R., 1992. Stable carbon isotopic composition of lipids of hydrocarbon seep mussels and whitefish, carbon flow implications. Transaction, Gulf Coast Association of Geological Societies 41, 467-472

108. Fang, J., 1991. Isotopic evidence for petroleum-derived carbonates in the Gulf of Mexico.  Transaction, Gulf Coast Association of Geological Societies 40, 276-282

109. Fang, J., Sassen, R., Nunn, J., and Roberts., H. H., 1990. Organic geochemistry of sediments of the deep-water Gulf of Mexico. Organic Geochemistry 14, 679

110. Lin, J. and Fang, J., 1985. Relationship of the characteristics of oilfield brines and distribution of oil and gas fields in eastern China. Minerals and Rocks 23, 65-76. (in Chinese)

九、专利

（1）陈家旺，王豪，方玉平，周朋，方家松，秦华伟，一种双向密封活塞式深渊多细胞生物诱捕及保真取样器，申请号：CN201911274659.5

（2）梁箫、彭莉华、陈珂、魏玉利、方家松、杨金龙. 一株深海芽孢杆菌及其在诱导厚壳贻贝稚贝附着方面的应用. 申请号：201810423184.0

（3）梁箫、彭莉华、张秀坤、魏玉利、方家松、杨金龙. 一株深海盐单胞菌及其在诱导厚壳贻贝稚贝附着方面的应用. 申请号：201810315970.9

（4）杨金龙、彭莉华、杨丽婷、魏玉利、方家松、梁箫. 一株海洋除烃海杆细菌及其在诱导厚壳贻贝稚贝附着方面的应用. 申请号：201810316697.1

（5）谢喆，闫方方，方家松。高产低温过氧化氢酶的希瓦氏菌WP3突变菌株及其构建方法和应用，申请号：202010264312.9

（6）谢喆，闫方方，方家松。重组低温过氧化氢酶及其重组载体和工程菌，申请号：202010264323.7